Rolapitant hydrochloride ( —— )

Catalog No. M17656 CAS No. 914462-92-3

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Product Name

Rolapitant hydrochloride
Note

Research use only, not for human use.
Brief Description

Rolapitant Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity.
Description

Rolapitant Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity.
Synonyms

——
Pathway

Endocrinology/Hormones
Target

Androgen Receptor (AR)
Recptor

NK1
Research Area

Others-Field
Indication

——

CAS Number

914462-92-3
Formula Weight

536.94
Molecular Formula

C25H27ClF6N2O2
Purity

98%
Solubility

——
SMILES

C[C@H](c1cc(cc(c1)C(F)(F)F)C(F)(F)F)OC[C@]1(CC[C@]2(CCC(=O)N2)CN1)c1ccccc1.Cl
Chemical Name

——

1.Rapoport B, Schwartzberg L, Chasen M, Powers D, Arora S, Navari R, Schnadig I. Eur J Cancer. 2016 Apr;57:23-30.

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